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Single α-particle irradiation permits real-time visualization of RNF8 accumulation at DNA damaged sites

As well as being a significant source of environmental radiation exposure, α-particles are increasingly considered for use in targeted radiation therapy. A better understanding of α-particle induced damage at the DNA scale can be achieved by following their tracks in real-time in targeted living cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Muggiolu, Giovanna, Pomorski, Michal, Claverie, Gérard, Berthet, Guillaume, Mer-Calfati, Christine, Saada, Samuel, Devès, Guillaume, Simon, Marina, Seznec, Hervé, Barberet, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282495/
https://ncbi.nlm.nih.gov/pubmed/28139723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41764
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