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QuickProbs 2: Towards rapid construction of high-quality alignments of large protein families

The ever-increasing size of sequence databases caused by the development of high throughput sequencing, poses to multiple alignment algorithms one of the greatest challenges yet. As we show, well-established techniques employed for increasing alignment quality, i.e., refinement and consistency, are...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Gudyś, Adam, Deorowicz, Sebastian
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282490/
https://ncbi.nlm.nih.gov/pubmed/28139687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41553
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