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Elevated regulatory T cells, surface and intracellular CTLA-4 expression and interleukin-17 in the lung cancer microenvironment in humans

Regulatory T cells (Tregs) play an important role in the suppression of the immune response in lung cancer. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) expressed on T lymphocytes is capable of downregulating cytotoxic T cells and is constitutively expressed on Tregs. Little is known about the populati...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Kwiecien, Iwona, Stelmaszczyk-Emmel, Anna, Polubiec-Kownacka, Malgorzata, Dziedzic, Dariusz, Domagala-Kulawik, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5281670/
https://ncbi.nlm.nih.gov/pubmed/27866241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1930-6
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