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DS28-6, a temperature-sensitive mutant of Chinese hamster ovary cells, expresses key phenotypic changes associated with brefeldin A treatment.

The temperature-sensitive Chinese hamster ovary (CHO) cell mutant DS28-6 has been previously shown to be pleiotropically defective in protein secretion. We have examined the mutant cells to determine the intracellular site of the block in secretion. By transmission electron microscopy a time-depende...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Zuber, C, Roth, J, Misteli, T, Nakano, A, Moremen, K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946407/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9818
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