L-citrulline prevents Asymmetric Dimethylarginine-Mediated reductions in Nitric Oxide and Nitrosative Stress In Primary Human Airway Epithelial Cells

INTRODUCTION: Asthma is associated with reduced systemic levels of L-arginine and increased asymmetric dimethylarginine (ADMA). This imbalance leads to nitric oxide synthase (NOS) uncoupling with reduced nitric oxide (NO) formation and greater oxidative and nitrosative stress. Whether this imbalance...

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Publicado en:Clin Exp Allergy
Main Authors: Winnica, Daniel, Que, Loretta G., Baffi, Cindy, Grasemann, Hartmut, Fiedler, Kaitlin, Yang, Zhonghui, Etling, Emily, Wasil, Karen, Wenzel, Sally E, Freeman, Bruce, Holguin, Fernando
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5280083/
https://ncbi.nlm.nih.gov/pubmed/27562295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12802
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