Antibodies to Infliximab Are Associated with Lower Infliximab Levels and Increased Likelihood of Surgery in Pediatric IBD

BACKGROUND: Adult studies suggest antibodies to infliximab (ATI) correlate with loss of response in inflammatory bowel disease but pediatric data are limited. METHODS: We conducted a cross-sectional study of trough infliximab levels and ATI in 134 pediatric and young adult patients receiving inflixi...

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Veröffentlicht in:Inflamm Bowel Dis
Hauptverfasser: Zitomersky, Naamah L., Atkinson, Benjamin J., Fournier, Kerri, Mitchell, Paul D., Stern, Julia Bender, Butler, Michael C., Ashworth, Lori, Hauenstein, Scott, Heiner, Linda, Chuang, Emil, Singh, Sharat, Bousvaros, Athos
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279914/
https://ncbi.nlm.nih.gov/pubmed/25569737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000284
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