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Differential pharmacology and clinical utility of sonidegib in advanced basal cell carcinoma

Patients suffering from advanced basal cell carcinoma (BCC) have very limited treatment options. Sonidegib selectively inhibits the growth of Hedgehog pathway-dependent tumors and can treat locally advanced BCC patients who are not candidates for surgery or radiation therapy. The BOLT clinical trial...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Wahid, Mohd, Jawed, Arshad, Dar, Sajad Ahmad, Mandal, Raju K, Haque, Shafiul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279825/
https://ncbi.nlm.nih.gov/pubmed/28182134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S97713
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