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Early BCR-ABL1 Transcript Decline after 1 Month of Tyrosine Kinase Inhibitor Therapy as an Indicator for Treatment Response in Chronic Myeloid Leukemia

In chronic myeloid leukemia (CML), early treatment prediction is important to identify patients with inferior overall outcomes. We examined the feasibility of using reductions in BCR-ABL1 transcript levels after 1 month of tyrosine kinase inhibitor (TKI) treatment to predict therapy response. Fifty-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: El Missiry, Mohamed, Hjorth-Hansen, Henrik, Richter, Johan, Olson-Strömberg, Ulla, Stenke, Leif, Porkka, Kimmo, Kreutzman, Anna, Mustjoki, Satu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279791/
https://ncbi.nlm.nih.gov/pubmed/28135325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171041
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