Inhibition of NF-κB Pathway and Modulation of MAPK Signaling Pathways in Glioblastoma and Implications for Lovastatin and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) Combination Therapy

Glioblastoma is a common malignant brain tumor and it is refractory to therapy because it usually contains a mixture of cell types. The tumor necrosis factor-related apoptosis inducing ligand (TRAIL) has been shown to induce apoptosis in a range of tumor cell types. Previously, we found that two hum...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Pi Chu, Lu, Gang, Deng, Yi, Wang, Cheng Dong, Su, Xian Wei, Zhou, Jing Ye, Chan, Tat Ming, Hu, Xiang, Poon, Wai Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279772/
https://ncbi.nlm.nih.gov/pubmed/28135339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171157
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