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Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering

Targeted genome editing has become a powerful genetic tool for studying gene function or for modifying genomes by correcting defective genes or introducing genes. A variety of reagents have been developed in recent years that can generate targeted double-stranded DNA cuts which can be repaired by th...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Guha, Tuhin Kumar, Wai, Alvan, Hausner, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279741/
https://ncbi.nlm.nih.gov/pubmed/28179977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2016.12.006
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