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Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypes.

We have identified three polymorphic microsatellites (which we call TNFa, TNFb, and TNFc) within a 12-kilobase region of the human major histocompatibility complex (MHC) that includes the tumor necrosis factor (TNF) locus. TNFc is located within the first intron of the TNF-beta gene and has only 2 a...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Jongeneel, C V, Briant, L, Udalova, I A, Sevin, A, Nedospasov, S A, Cambon-Thomsen, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52790/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946393/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9717
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