Virological efficacy of 24-week fozivudine-based regimen in ART-naive patients from Tanzania and Côte d’Ivoire

OBJECTIVE: Use of zidovudine (ZDV) in antiretroviral therapy is limited by toxicity and twice daily (b.i.d.) dosing. Fozivudine (FZD) is a ZDV prodrug, which is activated intracellularly to ZDV-monophosphate especially in mononuclear cells but not in bone marrow cells. FZD promises improved myelotox...

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Bibliografiske detaljer
Udgivet i:AIDS
Main Authors: Kroidl, Arne, Ello, Frederic, Mgaya, Jimson, Lennemann, Tessa, Moh, Raoul, Maganga, Lucas, Eholie, Serge, Pruvost, Alain, Saathoff, Elmar, Girard, Pierre-Marie, Zuhse, Ralph, von Massow, Friedrich, Anglaret, Xavier, Hoelscher, Michael, Danel, Christine
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2017
Fag:
Clinical Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278894/
https://ncbi.nlm.nih.gov/pubmed/27941394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001362
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