Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo

The cause-and-effect relationship between innate immune activation and neurodegeneration has been difficult to prove in complex animal models and patients. Here we review findings from a model of direct innate immune activation via CD14 stimulation using intracerebroventricular injection of lipopoly...

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Autors principals: Milatovic, Dejan, Zaja-Milatovic, Snjezana, Montine, Kathleen S, Shie, Feng-Shiun, Montine, Thomas J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC527876/
https://ncbi.nlm.nih.gov/pubmed/15498098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-1-20
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