Using In Vitro Dynamic Models To Evaluate Fluoroquinolone Activity against Emergence of Resistant Salmonella enterica Serovar Typhimurium

The objectives of this study were to determine pharmacokinetic/pharmacodynamic (PK/PD) indices of fluoroquinolones that minimize the emergence of resistant Salmonella enterica serovar Typhimurium (S. Typhimurium) using in vitro dynamic models and to establish mechanisms of resistance. Three fluoroqu...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Lee, Seung-Jin, Awji, Elias Gebru, Park, Na-hye, Park, Seung-Chun
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278752/
https://ncbi.nlm.nih.gov/pubmed/27895011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01756-16
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