In Vitro Exposure to Increasing Micafungin Concentrations Easily Promotes Echinocandin Resistance in Candida glabrata Isolates

We assessed the in vitro susceptibility of five echinocandin-susceptible Candida glabrata isolates after exposure to micafungin. The direct exposure to plates at different micafungin concentrations resulted in the inhibition of growth at 0.062 μg/ml. The progressive exposure was performed on plates...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Bordallo-Cardona, María Ángeles, Escribano, Pilar, de la Pedrosa, Elia Gómez G., Marcos-Zambrano, Laura Judith, Cantón, Rafael, Bouza, Emilio, Guinea, Jesús
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278751/
https://ncbi.nlm.nih.gov/pubmed/27872063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01542-16
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