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Statistical design considerations for pilot studies transitioning therapies from the bench to the bedside
Pilot studies are often used to transition therapies developed using animal models to a clinical setting. Frequently, the focus of such trials is on estimating the safety in terms of the occurrence of certain adverse events. With relatively small sample sizes, the probability of observing even relat...
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Hoofdauteurs: | , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
BioMed Central
2004
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC527875/ https://ncbi.nlm.nih.gov/pubmed/15511289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-2-37 |
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