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Statistical design considerations for pilot studies transitioning therapies from the bench to the bedside

Pilot studies are often used to transition therapies developed using animal models to a clinical setting. Frequently, the focus of such trials is on estimating the safety in terms of the occurrence of certain adverse events. With relatively small sample sizes, the probability of observing even relat...

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Bibliografische gegevens
Hoofdauteurs: Carter, Rickey E, Woolson, Robert F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC527875/
https://ncbi.nlm.nih.gov/pubmed/15511289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-2-37
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