High-Throughput Screening and Prediction Model Building for Novel Hemozoin Inhibitors Using Physicochemical Properties

It is essential to continue the search for novel antimalarial drugs due to the current spread of resistance against artemisinin by Plasmodium falciparum parasites. In this study, we developed in silico models to predict hemozoin inhibitors as a potential first-step screening for novel antimalarials....

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Huy, Nguyen Tien, Chi, Pham Lan, Nagai, Jun, Dang, Tran Ngoc, Mbanefo, Evaristus Chibunna, Ahmed, Ali Mahmoud, Long, Nguyen Phuoc, Thoa, Le Thi Bich, Hung, Le Phi, Titouna, Afaf, Kamei, Kaeko, Ueda, Hiroshi, Hirayama, Kenji
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278743/
https://ncbi.nlm.nih.gov/pubmed/27919903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01607-16
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