Inhibition of Plasmodium Liver Infection by Ivermectin

Avermectins are powerful endectocides with an established potential to reduce the incidence of vector-borne diseases. Here, we show that several avermectins inhibit the hepatic stage of Plasmodium infection in vitro. Notably, ivermectin potently inhibits liver infection in vivo by impairing parasite...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Mendes, António M., Albuquerque, Inês S., Machado, Marta, Pissarra, Joana, Meireles, Patrícia, Prudêncio, Miguel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278742/
https://ncbi.nlm.nih.gov/pubmed/27895022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02005-16
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