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High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation

During meiosis, cohesin complexes mediate sister chromatid cohesion (SCC), synaptonemal complex (SC) assembly and synapsis. Here, using super‐resolution microscopy, we imaged sister chromatid axes in mouse meiocytes that have normal or reduced levels of cohesin complexes, assessing the relationship...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Agostinho, Ana, Manneberg, Otto, van Schendel, Robin, Hernández‐Hernández, Abrahan, Kouznetsova, Anna, Blom, Hans, Brismar, Hjalmar, Höög, Christer
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278604/
https://ncbi.nlm.nih.gov/pubmed/27170622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642030
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