Human alpha-L-iduronidase: cDNA isolation and expression.

alpha-L-Iduronidase (IDUA; EC 3.2.1.76) is a lysosomal hydrolase in the metabolic pathway responsible for the degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. A deficiency of IDUA in humans leads to the accumulation of these glycosaminoglycans and results in the lysosomal...

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Autors principals: Scott, H S, Anson, D S, Orsborn, A M, Nelson, P V, Clements, P R, Morris, C P, Hopwood, J J
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC52785/
https://ncbi.nlm.nih.gov/pubmed/1946389
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