Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation

The signaling mechanisms that choreograph the assembly of the highly asymmetric pre- and postsynaptic structures are still poorly defined. Using synaptosome fractionation, immunostaining, and coimmunoprecipitation, we found that Celsr3 and Vangl2, core components of the planar cell polarity (PCP) pa...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Thakar, Sonal, Wang, Liqing, Yu, Ting, Ye, Mao, Onishi, Keisuke, Scott, John, Qi, Jiaxuan, Fernandes, Catarina, Han, Xuemei, Yates, John R., Berg, Darwin K., Zou, Yimin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278468/
https://ncbi.nlm.nih.gov/pubmed/28057866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612062114
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