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First-passage time approach to controlling noise in the timing of intracellular events

In the noisy cellular environment, gene products are subject to inherent random fluctuations in copy numbers over time. How cells ensure precision in the timing of key intracellular events despite such stochasticity is an intriguing fundamental problem. We formulate event timing as a first-passage t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ghusinga, Khem Raj, Dennehy, John J., Singh, Abhyudai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278449/
https://ncbi.nlm.nih.gov/pubmed/28069947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609012114
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