The thymine-thymine pyrimidine-pyrimidone(6-4) ultraviolet light photoproduct is highly mutagenic and specifically induces 3' thymine-to-cytosine transitions in Escherichia coli.

We have constructed single-stranded, M13-based vectors that contain a specifically located thymine-thymine pyrimidine-pyrimidone(6-4) UV photoproduct and have used these to estimate the frequency and accuracy of DNA replication past this adduct in uvrA6 cells of Escherichia coli. Both the normal and...

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Sonraí Bibleagrafaíochta
Main Authors: LeClerc, J E, Borden, A, Lawrence, C W
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1991
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC52783/
https://ncbi.nlm.nih.gov/pubmed/1946387
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