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Molecular Imaging Markers to Track Huntington’s Disease Pathology
Huntington’s disease (HD) is a progressive, monogenic dominant neurodegenerative disorder caused by repeat expansion mutation in the huntingtin gene. The accumulation of mutant huntingtin protein, forming intranuclear inclusions, subsequently leads to degeneration of medium spiny neurons in the stri...
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| Publié dans: | Front Neurol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278260/ https://ncbi.nlm.nih.gov/pubmed/28194132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00011 |
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