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Molecular Imaging Markers to Track Huntington’s Disease Pathology
Huntington’s disease (HD) is a progressive, monogenic dominant neurodegenerative disorder caused by repeat expansion mutation in the huntingtin gene. The accumulation of mutant huntingtin protein, forming intranuclear inclusions, subsequently leads to degeneration of medium spiny neurons in the stri...
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| 出版年: | Front Neurol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278260/ https://ncbi.nlm.nih.gov/pubmed/28194132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00011 |
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