Molecular Imaging Markers to Track Huntington’s Disease Pathology

Huntington’s disease (HD) is a progressive, monogenic dominant neurodegenerative disorder caused by repeat expansion mutation in the huntingtin gene. The accumulation of mutant huntingtin protein, forming intranuclear inclusions, subsequently leads to degeneration of medium spiny neurons in the stri...

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Udgivet i:Front Neurol
Main Authors: Wilson, Heather, De Micco, Rosa, Niccolini, Flavia, Politis, Marios
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278260/
https://ncbi.nlm.nih.gov/pubmed/28194132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00011
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