Anti-TNF-Mediated Modulation of Prohepcidin Improves Iron Availability in Inflammatory Bowel Disease, in an IL-6-Mediated Fashion

Background. Anaemia is common in inflammatory bowel disease (IBD), frequently resulting from a combination of iron deficiency and of anaemia of chronic disease (ACD). ACD is characterized by macrophage iron retention induced by proinflammatory cytokines. Hepcidin is the master inducer of iron accumu...

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Vydáno v:Can J Gastroenterol Hepatol
Hlavní autoři: Cavallaro, Flaminia, Duca, Lorena, Pisani, Laura Francesca, Rigolini, Roberta, Spina, Luisa, Tontini, Gian Eugenio, Munizio, Nadia, Costa, Elena, Cappellini, Maria Domenica, Vecchi, Maurizio, Pastorelli, Luca
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2017
Témata:
Clinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278212/
https://ncbi.nlm.nih.gov/pubmed/28191453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6843976
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