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Rescue of synthetic analogs of respiratory syncytial virus genomic RNA and effect of truncations and mutations on the expression of a foreign reporter gene.

The viral genomic RNA (vRNA) of human respiratory syncytial virus is a nonsegmented negative strand that is not infectious alone. To develop methods for complementing synthetic vRNA with viral proteins, a cDNA was constructed to encode a vRNA in which all of the viral protein-coding sequences were r...

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Bibliographic Details
Main Authors: Collins, P L, Mink, M A, Stec, D S
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC52778/
https://ncbi.nlm.nih.gov/pubmed/1946383
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