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Modulation of Replicative Lifespan in Cryptococcus neoformans: Implications for Virulence

The fungal pathogen, Cryptococcus neoformans, has been shown to undergo replicative aging. Old cells are characterized by advanced generational age and phenotypic changes that appear to mediate enhanced resistance to host and antifungal-based killing. As a consequence of this age-associated resilien...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Bouklas, Tejas, Jain, Neena, Fries, Bettina C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5276861/
https://ncbi.nlm.nih.gov/pubmed/28194146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00098
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