Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence

Using a valid chronic mild stress (CMS) model of depression, we found that adolescent (postnatal days [PND] 28–41) CMS induced transient alterations in anhedonia that did not persist into adulthood after a 3-week recovery period. Previously stressed adult rats exhibited more immobility/despair behav...

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Bibliographic Details
Published in:Neural Plast
Main Authors: Zhang, Yu, Shao, Feng, Wang, Qiong, Xie, Xi, Wang, Weiwen
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274659/
https://ncbi.nlm.nih.gov/pubmed/28182105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9382797
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