Distinct mechanisms underlying cholesterol protection against alcohol-induced BK channel inhibition and resulting vasoconstriction

Alcohol (ethanol) at concentrations reached in blood following moderate to heavy drinking (30–80 mM) reduces cerebral artery diameter via inhibition of voltage- and calcium-gated potassium channels of large conductance (BK) in cerebral artery smooth muscle. These channels consist of channel-forming...

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Bibliografiska uppgifter
I publikationen:Biochim Biophys Acta
Huvudupphovsmän: Bisen, Shivantika, Seleverstov, Olga, Belani, Jitendra, Rychnovsky, Scott, Dopico, Alex M., Bukiya, Anna N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274633/
https://ncbi.nlm.nih.gov/pubmed/27565113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2016.08.013
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