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Gene targeting in Chinese hamster ovary cells is conservative.

Two fundamentally different pathways for homologous recombination have been identified in mammalian cells. For most chromosomal recombination events, two copies of a homologous sequence recombine to yield two copies in the products; such events are said to be conservative because the number of copie...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pennington, S L, Wilson, J H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946364/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9498
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