Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence.
The murine alpha 1-protease inhibitors (alpha 1-PI) are encoded by a small gene family on chromosome 12. Studies of alpha 1-PI and other serine protease inhibitor genes have revealed an unusually high rate of mutation of the reactive centers of the inhibitors. Using a modification of the PCR techniq...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52728/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9417 |
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