Isolation of temperature-sensitive mutations of the tyrosine kinase receptor sevenless (sev) in Drosophila and their use in determining its time of action.
Loss-of-function mutations in the sevenless (sev) gene in Drosophila result in the failure to differentiate a specific photoreceptor cell type--namely, the R7 cell. The sev gene encodes a cell-surface receptor tyrosine kinase that functions in the presumptive R7 cell to transduce developmental cues...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1991
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9387 |
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