Noninvasive detection of changes in membrane potential in cultured neurons by light scattering.

We report a procedure to detect electrical activity in cultured neurons by changes in their intrinsic optical properties. Using dark-field microscopy to detect scattered light, we observe an optical signal that is linearly proportional to the change in the membrane potential. Action potentials can b...

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Библиографические подробности
Главные авторы: Stepnoski, R A, LaPorta, A, Raccuia-Behling, F, Blonder, G E, Slusher, R E, Kleinfeld, D
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC52721/
https://ncbi.nlm.nih.gov/pubmed/1946349
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