Leishmania HASP and SHERP Genes Are Required for In Vivo Differentiation, Parasite Transmission and Virulence Attenuation in the Host

Differentiation of extracellular Leishmania promastigotes within their sand fly vector, termed metacyclogenesis, is considered to be essential for parasites to regain mammalian host infectivity. Metacyclogenesis is accompanied by changes in the local parasite environment, including secretion of comp...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Doehl, Johannes S. P., Sádlová, Jovana, Aslan, Hamide, Pružinová, Kateřina, Metangmo, Sonia, Votýpka, Jan, Kamhawi, Shaden, Volf, Petr, Smith, Deborah F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271408/
https://ncbi.nlm.nih.gov/pubmed/28095465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006130
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