Leishmania HASP and SHERP Genes Are Required for In Vivo Differentiation, Parasite Transmission and Virulence Attenuation in the Host

Differentiation of extracellular Leishmania promastigotes within their sand fly vector, termed metacyclogenesis, is considered to be essential for parasites to regain mammalian host infectivity. Metacyclogenesis is accompanied by changes in the local parasite environment, including secretion of comp...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Doehl, Johannes S. P., Sádlová, Jovana, Aslan, Hamide, Pružinová, Kateřina, Metangmo, Sonia, Votýpka, Jan, Kamhawi, Shaden, Volf, Petr, Smith, Deborah F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271408/
https://ncbi.nlm.nih.gov/pubmed/28095465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006130
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