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Altered stoichiometry and nuclear delocalization of NonO and PSF promote cellular senescence

While cellular senescence is a critical mechanism to prevent malignant transformation of potentially mutated cells, persistence of senescent cells can also promote cancer and aging phenotypes. NonO/p54nrb and PSF are multifunctional hnRNPs typically found as a complex exclusively within the nuclei o...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Huang, Ching-Jung, Das, Utsab, Xie, Weijun, Ducasse, Miryam, Tucker, Haley O.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270673/
https://ncbi.nlm.nih.gov/pubmed/27992859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101125
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