Endoplasmic Reticulum Stress and Ca(2+) Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism

Accumulating evidence implicates endoplasmic reticulum (ER) stress as a mediator of impaired lipid metabolism, thereby contributing to fatty liver disease and atherosclerosis. Previous studies demonstrated that ER stress can activate the sterol regulatory element-binding protein-2 (SREBP2), an ER-lo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lebeau, Paul, Al-Hashimi, Ali, Sood, Sudesh, Lhoták, Šárka, Yu, Pei, Gyulay, Gabriel, Paré, Guillaume, Chen, S. R. Wayne, Trigatti, Bernardo, Prat, Annik, Seidah, Nabil G., Austin, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270491/
https://ncbi.nlm.nih.gov/pubmed/27909053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744235
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados