A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury

Astrogliosis (i.e. glial scar), which is comprised primarily of proliferated astrocytes at the lesion site and migrated astrocytes from neighboring regions, is one of the key reactions in determining outcomes after CNS injury. In an effort to identify potential molecules/pathways that regulate astro...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ishii, Taiji, Ueyama, Takehiko, Shigyo, Michiko, Kohta, Masaaki, Kondoh, Takeshi, Kuboyama, Tomoharu, Uebi, Tatsuya, Hamada, Takeshi, Gutmann, David H., Aiba, Atsu, Kohmura, Eiji, Tohda, Chihiro, Saito, Naoaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270470/
https://ncbi.nlm.nih.gov/pubmed/27941025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748871
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