HERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features

BACKGROUND: Melanoma is a heterogeneous tumor in which phenotype-switching and CD133 marker have been associated with metastasis promotion and chemotherapy resistance. CD133 positive (CD133+) subpopulation has also been suggested as putative cancer stem cell (CSC) of melanoma tumor. Human endogenous...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Argaw-Denboba, Ayele, Balestrieri, Emanuela, Serafino, Annalucia, Cipriani, Chiara, Bucci, Ilaria, Sorrentino, Roberta, Sciamanna, Ilaria, Gambacurta, Alessandra, Sinibaldi-Vallebona, Paola, Matteucci, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270369/
https://ncbi.nlm.nih.gov/pubmed/28125999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0485-x
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