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Model‐Based Population Pharmacokinetic Analysis of Nivolumab in Patients With Solid Tumors
Nivolumab is a fully human monoclonal antibody that inhibits programmed death‐1 activation. The clinical pharmacology profile of nivolumab was analyzed by a population pharmacokinetics model that assessed covariate effects on nivolumab concentrations in 1,895 patients who received 0.3–10.0 mg/kg niv...
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| Publicado no: | CPT Pharmacometrics Syst Pharmacol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270302/ https://ncbi.nlm.nih.gov/pubmed/28019091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12143 |
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