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Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.

The bacterial superantigen staphylococcal enterotoxin (SE) A (SEA) directs cytotoxic T lymphocytes (CTLs) expressing particular sequences of the T-cell receptor (TCR) beta chain to lyse tumor cells expressing major histocompatibility complex (MHC) class II molecules, which serve as receptors for SEs...

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Autors principals: Dohlsten, M, Hedlund, G, Akerblom, E, Lando, P A, Kalland, T
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC52699/
https://ncbi.nlm.nih.gov/pubmed/1924393
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