GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome

Epigenetic inactivation of GPX3 has been identified in various cancers including leukemia. Moreover, aberrant DNA methylation was also found as a dominant mechanism of disease progression in myelodysplastic syndrome (MDS). This study intended to explore GPX3 promoter methylation and its clinical rel...

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Foilsithe in:Cancer Med
Main Authors: Zhou, Jing‐Dong, Lin, Jiang, Zhang, Ting‐Juan, Ma, Ji‐Chun, Yang, Lei, Wen, Xiang‐Mei, Guo, Hong, Yang, Jing, Deng, Zhao‐Qun, Qian, Jun
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Cancer Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269561/
https://ncbi.nlm.nih.gov/pubmed/27891827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.984
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