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A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12.

Melanocytes preferentially express an mRNA species, Pmel 17, whose protein product cross-reacts with anti-tyrosinase antibodies and whose expression correlates with the melanin content. We have now analyzed the deduced protein structure and mapped its chromosomal location in mouse and human. The ami...

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Bibliografiske detaljer
Main Authors: Kwon, B S, Chintamaneni, C, Kozak, C A, Copeland, N G, Gilbert, D J, Jenkins, N, Barton, D, Francke, U, Kobayashi, Y, Kim, K K
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52687/
https://ncbi.nlm.nih.gov/pubmed/1924386
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