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Fluoride Regulate Osteoblastic Transforming Growth Factor-β1 Signaling by Mediating Recycling of the Type I Receptor ALK5

This study aimed to preliminary investigate the role of activin receptor-like kinase (ALK) 5 as one of TGF-βR1 subtypes in bone turnover and osteoblastic differentiation induced by fluoride. We analyzed bone mineral density and the expression of genes related with transforming growth factor-β1(TGF-β...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yang, Chen, Wang, Yan, Xu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268439/
https://ncbi.nlm.nih.gov/pubmed/28125630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170674
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