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Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting

BACKGROUND: Aggregation of peptide hormone precursors in the trans-Golgi network is an essential process in the biogenesis of secretory granules in endocrine cells. It has recently been proposed that this aggregation corresponds to the formation of functional amyloids. Our previous finding that domi...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Beuret, Nicole, Hasler, Franziska, Prescianotto-Baschong, Cristina, Birk, Julia, Rutishauser, Jonas, Spiess, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267430/
https://ncbi.nlm.nih.gov/pubmed/28122547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0347-9
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