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Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting

BACKGROUND: Aggregation of peptide hormone precursors in the trans-Golgi network is an essential process in the biogenesis of secretory granules in endocrine cells. It has recently been proposed that this aggregation corresponds to the formation of functional amyloids. Our previous finding that domi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Biol
Prif Awduron: Beuret, Nicole, Hasler, Franziska, Prescianotto-Baschong, Cristina, Birk, Julia, Rutishauser, Jonas, Spiess, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267430/
https://ncbi.nlm.nih.gov/pubmed/28122547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0347-9
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