Preferential T-cell receptor beta-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis.

Multiple sclerosis is an autoimmune disease in which T lymphocytes reactive to myelin basic protein (BP) could play a central role. T cells specific for BP were cloned from the blood of multiple sclerosis patients and normal individuals, and expression of T-cell receptor variable region genes was an...

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Autori principali: Kotzin, B L, Karuturi, S, Chou, Y K, Lafferty, J, Forrester, J M, Better, M, Nedwin, G E, Offner, H, Vandenbark, A A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC52672/
https://ncbi.nlm.nih.gov/pubmed/1717998
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