Sitagliptin treatment after total pancreatectomy with islet autotransplantation: A randomized, placebo-controlled study

Insulin independence after total pancreatectomy and islet autotransplant (TPIAT) for chronic pancreatitis is limited by a high rate of post-procedure beta cell apoptosis. Endogenous GLP-1 and GIP, which are increased by DPP-4 inhibitor therapy (sitagliptin) may protect against beta cell apoptosis. T...

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Bibliographic Details
Published in:Am J Transplant
Main Authors: Bellin, Melena D., Beilman, Greg J., Dunn, Ty B., Pruett, Timothy L., Sutherland, David E.R., Chinnakotla, Srinath, Hodges, James S., Lane, Audrey, Ptacek, Peggy, Berry, K. Louise, Hering, Bernhard J., Moran, Antoinette
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266635/
https://ncbi.nlm.nih.gov/pubmed/27459721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13979
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