Sitagliptin treatment after total pancreatectomy with islet autotransplantation: A randomized, placebo-controlled study

Insulin independence after total pancreatectomy and islet autotransplant (TPIAT) for chronic pancreatitis is limited by a high rate of post-procedure beta cell apoptosis. Endogenous GLP-1 and GIP, which are increased by DPP-4 inhibitor therapy (sitagliptin) may protect against beta cell apoptosis. T...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Bellin, Melena D., Beilman, Greg J., Dunn, Ty B., Pruett, Timothy L., Sutherland, David E.R., Chinnakotla, Srinath, Hodges, James S., Lane, Audrey, Ptacek, Peggy, Berry, K. Louise, Hering, Bernhard J., Moran, Antoinette
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266635/
https://ncbi.nlm.nih.gov/pubmed/27459721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13979
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