Sitagliptin treatment after total pancreatectomy with islet autotransplantation: A randomized, placebo-controlled study

Insulin independence after total pancreatectomy and islet autotransplant (TPIAT) for chronic pancreatitis is limited by a high rate of post-procedure beta cell apoptosis. Endogenous GLP-1 and GIP, which are increased by DPP-4 inhibitor therapy (sitagliptin) may protect against beta cell apoptosis. T...

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Veröffentlicht in:Am J Transplant
Hauptverfasser: Bellin, Melena D., Beilman, Greg J., Dunn, Ty B., Pruett, Timothy L., Sutherland, David E.R., Chinnakotla, Srinath, Hodges, James S., Lane, Audrey, Ptacek, Peggy, Berry, K. Louise, Hering, Bernhard J., Moran, Antoinette
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266635/
https://ncbi.nlm.nih.gov/pubmed/27459721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13979
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