Sitagliptin treatment after total pancreatectomy with islet autotransplantation: A randomized, placebo-controlled study

Insulin independence after total pancreatectomy and islet autotransplant (TPIAT) for chronic pancreatitis is limited by a high rate of post-procedure beta cell apoptosis. Endogenous GLP-1 and GIP, which are increased by DPP-4 inhibitor therapy (sitagliptin) may protect against beta cell apoptosis. T...

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發表在:Am J Transplant
Main Authors: Bellin, Melena D., Beilman, Greg J., Dunn, Ty B., Pruett, Timothy L., Sutherland, David E.R., Chinnakotla, Srinath, Hodges, James S., Lane, Audrey, Ptacek, Peggy, Berry, K. Louise, Hering, Bernhard J., Moran, Antoinette
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266635/
https://ncbi.nlm.nih.gov/pubmed/27459721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13979
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