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Differential Effects Of Aprepitant, A Clinically Used Neurokinin-1 Receptor Antagonist On The Expression Of Conditioned Psychostimulant Versus Opioid Reward

RATIONALE: Neurokinin-1 receptor (NK1R) signaling modulates behaviors associated with psychostimulants and opioids. Psychostimulants, such as amphetamine (AMPH) and cocaine, bind to monoamine transporters, and alter their functions. Both dopamine and norepinephrine transporters are regulated by NK1R...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Mannangatti, Padmanabhan, Sundaramurthy, Santhanalakshmi, Ramamoorthy, Sammanda, Jayanthi, Lankupalle D
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266628/
https://ncbi.nlm.nih.gov/pubmed/28013351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4504-6
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