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Whole Genome Survey of Copy Number Variation in the Spontaneously Hypertensive Rat: Relationship to Quantitative Trait Loci, Gene Expression and Blood Pressure

Copy number variation has recently emerged as an important genetic mechanism leading to phenotypic heterogeneity. The aim of our study was to determine whether copy number variants (CNVs) exist between the SHR and its control strain - the Wistar-Kyoto (WKY) rat, whether these map to quantitative tra...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Charchar, Fadi J, Kaiser, Michael, Bingham, Andrew J, Fotinatos, Nina, Ahmady, Fahima, Tomaszewski, Maciej, Samani, Nilesh J
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266550/
https://ncbi.nlm.nih.gov/pubmed/20231529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.141663
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